Thursday, December 12, 2019

DNA and Protein-Examples-Free-Samples for Students-Myassignment

Question: Discuss about the Amino Acid. Answer Introduction Examples of amino acids include the DNA and the changes in this amino acid lead to an altered phenotype. For instance, the changes of a phenotype to a wild or mutant type may be because of the changes in the mutant allele or other genes.( Ng, 2003) Peer Reviewed Articles on Amino Acid Changes Leading To An Altered Phenotype Some scholarly publications have reported some of threw theoretical work as well as empirical work on the amino acids changes that may lead to the altered phenotype. The scholarly works are listed below: Aebersold, R. and Mann, M., 2016. Mass-spectrometric exploration of proteome structure and function. Nature, 537(7620), pp.347-355. Lynch, C.J. and Adams, S.H., 2014. Branched-chain amino acids in metabolic signalling and insulin resistance. Nature Reviews Endocrinology, 10(12), pp.723-736. Ng, P.C. and Henikoff, S., 2003. SIFT: Predicting amino acid changes that affect protein function. Nucleic acids research, 31(13), pp.3812-3814. Raichur, S., Wang, S.T., Chan, P.W., Li, Y., Ching, J., Chaurasia, B., Dogra, S., hman, M.K., Takeda, K., Sugii, S. and Pewzner-Jung, Y., 2014. CerS2 haploinsufficiency inhibits -oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. Cell metabolism, 20(4), pp.687-695. Rutsch, F., MacDougall, M., Lu, C., Buers, I., Mamaeva, O., Nitschke, Y., Rice, G.I., Erlandsen, H., Kehl, H.G., Thiele, H. and Nrnberg, P., 2015. A specific IFIH1 gain-of-function mutation causes Singleton-Merten syndrome. The American Journal of Human Genetics, 96(2), pp.275-282. Protein Examples There are varieties of proteins both human as well as microbial. One of the m is the peptide, which has 10 to 150 amino acids. Casein is also an example of protein, which comes from milk. Others include insulin, antibodies, hemoglobin, keratin as well as the receptor proteins.( Figurski, 2013) References Figurski, D., 2013. Genetic Manipulation of DNA and Protein-Examples from Current Researc. InTech,. Ng, P.C. and Henikoff, S., 2003. SIFT: Predicting amino acid changes that affect protein function. Nucleic acids research, 31(13), pp.3812-3814

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